CXCL8 in Tumor Biology and Its Implications for Clinical Translation

CXCL8 in Tumor Biology and Its Implications for Clinical Translation

The chemokine CXCL8 has been found to play an important role in tumor progression in recent years. CXCL8 activates multiple intracellular signaling pathways by binding to its receptors (CXCR1/2), and plays dual pro-tumorigenic roles in the tumor microenvironment (TME) including directly promoting tu...

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Bibliographic Details
Main Authors: Xingyu Xiong, Xinyang Liao, Shi Qiu, Hang Xu, Shiyu Zhang, Sheng Wang, Jianzhong Ai, Lu Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
CXCL8
tumor microenvironment
tumor progression
tumor immune suppression
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.723846/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2022.723846/full

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