A matrigel-free method for culture of pancreatic endocrine-like cells in defined protein-based hydrogels

A matrigel-free method for culture of pancreatic endocrine-like cells in defined protein-based hydrogels

The transplantation of pancreatic endocrine islet cells from cadaveric donors is a promising treatment for type 1 diabetes (T1D), which is a chronic autoimmune disease that affects approximately nine million people worldwide. However, the demand for donor islets outstrips supply. This problem could...

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Bibliographic Details
Main Authors: Mark T. Kozlowski, Heather N. Zook, Desnor N. Chigumba, Christopher P. Johnstone, Luis F. Caldera, Hung-Ping Shih, David A. Tirrell, Hsun Teresa Ku
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
defined culture medium
endocrine cells
matrigel-free culture
pancreatic development
protein-based culture
pancreatic organoid
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1144209/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1144209/full

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