CD6-mediated inhibition of T cell activation via modulation of Ras
Abstract Background CD6 is one of many cell surface receptors known to regulate signal transduction upon T cell activation. However, whether CD6 mediates costimulatory or inhibitory signals is controversial. When T cells engage with antigen presenting cells (APCs), CD6 interacts with its ligand CD16...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-11-01
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Series: | Cell Communication and Signaling |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12964-022-00998-x |