CD6-mediated inhibition of T cell activation via modulation of Ras

CD6-mediated inhibition of T cell activation via modulation of Ras

Abstract Background CD6 is one of many cell surface receptors known to regulate signal transduction upon T cell activation. However, whether CD6 mediates costimulatory or inhibitory signals is controversial. When T cells engage with antigen presenting cells (APCs), CD6 interacts with its ligand CD16...

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Bibliographic Details
Main Authors: Sónia N. Henriques, Liliana Oliveira, Rita F. Santos, Alexandre M. Carmo
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Cell Communication and Signaling
Subjects:
Cell surface molecules
Inhibitory receptors
Signaling transduction
Immunological synapse
GTPases
FRET
Online Access:https://doi.org/10.1186/s12964-022-00998-x

Internet

https://doi.org/10.1186/s12964-022-00998-x

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