Nuclear receptor modulators inhibit osteosarcoma cell proliferation and tumour growth by regulating the mTOR signaling pathway

Nuclear receptor modulators inhibit osteosarcoma cell proliferation and tumour growth by regulating the mTOR signaling pathway

Abstract Osteosarcoma is the most common primary malignant bone tumour in children and adolescents. Chemoresistance leads to poor responses to conventional therapy in patients with osteosarcoma. The discovery of novel effective therapeutic targets and drugs is still the main focus of osteosarcoma re...

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Bibliographic Details
Main Authors: Baoshi Yuan, Kexin Shi, Juanmin Zha, Yujia Cai, Yue Gu, Kai Huang, Wenchang Yue, Qiaocheng Zhai, Ning Ding, Wenyan Ren, Weiqi He, Ying Xu, Tao Wang
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05545-7

Internet

https://doi.org/10.1038/s41419-022-05545-7

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