Genetic deletion of the 67‐kDa isoform of glutamate decarboxylase alters conditioned fear behavior in rats
The GABAergic system is thought to play an important role in the control of cognition and emotion, such as fear, and is related to the pathophysiology of psychiatric disorders. For example, the expression of the 67‐kDa isoform of glutamate decarboxylase (GAD67), a GABA‐producing enzyme, is downregul...
Main Authors: | Kazuyuki Fujihara, Takumi Sato, Yoshiki Miyasaka, Tomoji Mashimo, Yuchio Yanagawa |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2021-02-01
|
Series: | FEBS Open Bio |
Subjects: | |
Online Access: | https://doi.org/10.1002/2211-5463.13065 |
Similar Items
-
Impact of Dysfunctional Feed-Forward Inhibition on Glutamate Decarboxylase Isoforms and γ-Aminobutyric Acid Transporters
by: Sandesh Panthi, et al.
Published: (2021-07-01) -
Involvement of the GABAergic system in PTSD and its therapeutic significance
by: Junhui Huang, et al.
Published: (2023-02-01) -
Corrigendum: Involvement of the GABAergic system in PTSD and its therapeutic significance
by: Junhui Huang, et al.
Published: (2023-02-01) -
Activity dynamics of amygdala GABAergic neurons during cataplexy of narcolepsy
by: Ying Sun, et al.
Published: (2019-08-01) -
Insights into the leveraging of GABAergic signaling in cancer therapy
by: Tian‐Jiao Li, et al.
Published: (2023-07-01)