Performance and scalability of discriminative metrics for comparative gene identification in 12 Drosophila genomes.

Comparative genomics of multiple related species is a powerful methodology for the discovery of functional genomic elements, and its power should increase with the number of species compared. Here, we use 12 Drosophila genomes to study the power of comparative genomics metrics to distinguish between...

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Bibliographic Details
Main Authors: Michael F Lin, Ameya N Deoras, Matthew D Rasmussen, Manolis Kellis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2291194?pdf=render