Performance and scalability of discriminative metrics for comparative gene identification in 12 Drosophila genomes.

Comparative genomics of multiple related species is a powerful methodology for the discovery of functional genomic elements, and its power should increase with the number of species compared. Here, we use 12 Drosophila genomes to study the power of comparative genomics metrics to distinguish between...

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Detalles Bibliográficos
Main Authors: Michael F Lin, Ameya N Deoras, Matthew D Rasmussen, Manolis Kellis
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2008-04-01
Series:PLoS Computational Biology
Acceso en liña:http://europepmc.org/articles/PMC2291194?pdf=render