Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis

Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis

Mitochondria are crucial in sustaining and orchestrating cellular functions. Capitalizing on this, we explored mitochondrial transplantation as an innovative therapeutic strategy for acute spinal cord injury (SCI). In our study, we developed an engineered mitochondrial compound tailored to target ma...

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Bibliographic Details
Main Authors: Jiaqi Xu, Chaoran Shi, Feifei Yuan, Yinghe Ding, Yong Xie, Yudong Liu, Fengzhang Zhu, Hongbin Lu, Chunyue Duan, Jianzhong Hu, Liyuan Jiang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-02-01
Series:Bioactive Materials
Subjects:
Spinal cord injury (SCI)
Mitochondrial transplantation
Macrophage
Phagocytosis
Targeted therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23003316

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X23003316

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