Profiles and integration of the gut microbiome and fecal metabolites in severe intrahepatic cholestasis of pregnancy

Profiles and integration of the gut microbiome and fecal metabolites in severe intrahepatic cholestasis of pregnancy

Abstract Background The pathogenesis of intrahepatic cholestasis of pregnancy (ICP) remains unknown. The gut microbiome and its metabolites play important roles in bile acid metabolism, and previous studies have indicated the association of the gut microbiome with ICP. Methods We recruited a cohort...

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Bibliographic Details
Main Authors: Xiang Li, Han Xie, Jia-jing Chao, Yuan-Hui Jia, Jia Zuo, Yan-peng An, Yi-Rong Bao, Xiang Jiang, Hao Ying
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Microbiology
Subjects:
Intrahepatic cholestasis of pregnancy
Bile acid
Gut microbiome
16S rRNA
Metabolomics
MIMOSA model
Online Access:https://doi.org/10.1186/s12866-023-02983-x

Internet

https://doi.org/10.1186/s12866-023-02983-x

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