Peroxisome Proliferator-Activated Receptor-γ Modulates the Response of Macrophages to Lipopolysaccharide and Glucocorticoids

Peroxisome Proliferator-Activated Receptor-γ Modulates the Response of Macrophages to Lipopolysaccharide and Glucocorticoids

Although glucocorticoids (GC) represent the most frequently used immunosuppressive drugs, their effects are still not well understood. In our previous studies, we have shown that treatment of monocytes with GC does not cause a global suppression of monocytic effector functions, but rather induces di...

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Bibliographic Details
Main Authors: Michael Heming, Sandra Gran, Saskia-L. Jauch, Lena Fischer-Riepe, Antonella Russo, Luisa Klotz, Sven Hermann, Michael Schäfers, Johannes Roth, Katarzyna Barczyk-Kahlert
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
PPARgamma
glucocorticoids
macrophage
migration
anti-inflammatory
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00893/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00893/full

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