Binding of Pentagalloyl Glucose to Aortic Wall Proteins: Insights from Peptide Mapping and Simulated Docking Studies

Binding of Pentagalloyl Glucose to Aortic Wall Proteins: Insights from Peptide Mapping and Simulated Docking Studies

Pentagalloyl glucose (PGG) is currently being investigated as a non-surgical treatment for abdominal aortic aneurysms (AAAs); however, the molecular mechanisms of action of PGG on the AAA matrix components and the intra-luminal thrombus (ILT) still need to be better understood. To assess these inter...

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Bibliographic Details
Main Authors: Dan Simionescu, Nishanth Tharayil, Elizabeth Leonard, Wenda Carlyle, Alex Schwarz, Kelvin Ning, Christopher Carsten, Juan Carlos Carrillo Garcia, Alexander Carter, Collin Owens, Agneta Simionescu
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Bioengineering
Subjects:
aneurysms
polyphenols
diffusion
stabilization
docking simulations
elastin
Online Access:https://www.mdpi.com/2306-5354/10/8/936

Internet

https://www.mdpi.com/2306-5354/10/8/936

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