Prompt Graft Cooling Enhances Cardioprotection during Heart Transplantation Procedures through the Regulation of Mitophagy

Prompt Graft Cooling Enhances Cardioprotection during Heart Transplantation Procedures through the Regulation of Mitophagy

A complete and prompt cardiac arrest using a cold cardioplegic solution is routinely used in heart transplantation to protect the graft function. However, warm ischemic time is still inevitable during the procedure to isolate donor hearts in the clinical setting. Our knowledge of the mechanism chang...

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Bibliographic Details
Main Authors: Zhichao Wu, Jialiang Liang, Wei Huang, Lin Jiang, Christian Paul, Bonnie Lin, Junmeng Zheng, Yigang Wang
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
heart transplant
cardioplegic solution
ischemia-reperfusion
cardiac arrest
mitophagy
Online Access:https://www.mdpi.com/2073-4409/10/11/2912

Internet

https://www.mdpi.com/2073-4409/10/11/2912

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