Variation in Glucose-6-Phosphate Dehydrogenase activity following acute malaria

Primaquine and tafenoquine are the only licensed drugs with activity against Plasmodium vivax hypnozoites but cause haemolysis in patients with glucose–6–phosphate dehydrogenase (G6PD) deficiency. Malaria also causes haemolysis, leading to the replacement of older erythrocytes with low G6PD activity...

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Bibliographic Details
Main Authors: Benedikt Ley, Mohammad Shafiul Alam, Ari Winasti Satyagraha, Ching Swe Phru, Kamala Thriemer, Dagimawie Tadesse, Tamiru Shibiru, Asrat Hailu, Mohammad Golam Kibria, Mohammad Sharif Hossain, Hisni Rahmat, Jeanne R. Poespoprodjo, Wasif Ali Khan, Julie A. Simpson, Ric N. Price
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094517/?tool=EBI