Targeting HER2 in breast cancer: new drugs and paradigms on the horizon

About 15–20% of all breast cancers (BCs) are defined human epidermal growth factor receptor 2 (HER2)-positive, based on the overexpression of HER2 protein and/or amplification of ERBB2 gene. Such alterations lead to a more aggressive behavior of the disease, but also predict response to treatments t...

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Bibliographic Details
Main Authors: Paolo Tarantino, Stefania Morganti, Giuseppe Curigliano
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2021-04-01
Series:Exploration of Targeted Anti-tumor Therapy
Subjects:
Online Access:https://www.explorationpub.com/Journals/etat/Article/100237