In vitro characterization of [125I]HY-3-24, a selective ligand for the dopamine D3 receptor

In vitro characterization of [125I]HY-3-24, a selective ligand for the dopamine D3 receptor

IntroductionDopamine D3 receptor (D3R) ligands have been studied for the possible treatment of neurological and neuropsychiatric disorders. However, selective D3R radioligands for in vitro binding studies have been challenging to identify due to the high structural similarity between the D2R and D3R...

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Bibliographic Details
Main Authors: Ji Youn Lee, Ho Young Kim, Paul Martorano, Aladdin Riad, Michelle Taylor, Robert R. Luedtke, Robert H. Mach
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Neuroscience
Subjects:
[125I]HY-3-24
dopamine D3 receptor ligand
in vitro binding assay
islands of Calleja
nonhuman primates
autoradiography
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2024.1380009/full

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https://www.frontiersin.org/articles/10.3389/fnins.2024.1380009/full

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