An acid trip activates protumoral macrophages to promote hepatocellular carcinoma malignancy
Tumor-associated macrophages (TAMs) promote metastasis and tumor cell extravasation, survival, and growth. In hepatocellular carcinoma (HCC), the presence of TAM subpopulations correlates with poor outcome. In this issue of the JCI, Ning et al. report on their use of cell culture, mouse models, and...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical Investigation
2022-04-01
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Series: | The Journal of Clinical Investigation |
Online Access: | https://doi.org/10.1172/JCI158562 |