An acid trip activates protumoral macrophages to promote hepatocellular carcinoma malignancy

Tumor-associated macrophages (TAMs) promote metastasis and tumor cell extravasation, survival, and growth. In hepatocellular carcinoma (HCC), the presence of TAM subpopulations correlates with poor outcome. In this issue of the JCI, Ning et al. report on their use of cell culture, mouse models, and...

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Bibliographic Details
Main Authors: Nicola Graham, Jeffrey W. Pollard
Format: Article
Language:English
Published: American Society for Clinical Investigation 2022-04-01
Series:The Journal of Clinical Investigation
Online Access:https://doi.org/10.1172/JCI158562