Uncoupling protein 2 and aldolase B impact insulin release by modulating mitochondrial function and Ca2+ release from the ER

Uncoupling protein 2 and aldolase B impact insulin release by modulating mitochondrial function and Ca2+ release from the ER

Summary: Uncoupling protein 2 (UCP2), a mitochondrial protein, is known to be upregulated in pancreatic islets of patients with type 2 diabetes (T2DM); however, the pathological significance of this increase in UCP2 expression is unclear. In this study, we highlight the molecular link between the in...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Ryota Inoue, Takahiro Tsuno, Yu Togashi, Tomoko Okuyama, Aoi Sato, Kuniyuki Nishiyama, Mayu Kyohara, Jinghe Li, Setsuko Fukushima, Tatsuya Kin, Daisuke Miyashita, Yusuke Shiba, Yoshitoshi Atobe, Hiroshi Kiyonari, Kana Bando, A.M. James Shapiro, Kengo Funakoshi, Rohit N. Kulkarni, Yasuo Terauchi, Jun Shirakawa
Format: Artykuł
Język:English
Wydane: Elsevier 2022-07-01
Seria:iScience
Hasła przedmiotowe:
Endocrinology
cell biology
Functional aspects of cell biology
Dostęp online:http://www.sciencedirect.com/science/article/pii/S2589004222008756

Internet

http://www.sciencedirect.com/science/article/pii/S2589004222008756

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