Interleukin-10 Deficiency Impacts on TNF-Induced NFκB Regulated Responses In Vivo

Interleukin-10 Deficiency Impacts on TNF-Induced NFκB Regulated Responses In Vivo

Interleukin-10 (IL-10) is an anti-inflammatory cytokine that has a major protective role against intestinal inflammation. We recently revealed that intestinal epithelial cells in vitro regulate NFκB-driven transcriptional responses to TNF via an autocrine mechanism dependent on IL-10 secretion. Here...

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Bibliographic Details
Main Authors: Stamatia Papoutsopoulou, Liam Pollock, Jonathan M. Williams, Maya M. L. F. Abdul-Mahdi, Reyhaneh Dobbash, Carrie A. Duckworth, Barry J. Campbell
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biology
Subjects:
interleukin-10
intestine
mucosa
NFκB
RelA
tumour necrosis factor
Online Access:https://www.mdpi.com/2079-7737/11/10/1377

Internet

https://www.mdpi.com/2079-7737/11/10/1377

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