Human Mesenchymal Stem Cell‐Derived Miniature Joint System for Disease Modeling and Drug Testing

Human Mesenchymal Stem Cell‐Derived Miniature Joint System for Disease Modeling and Drug Testing

Abstract Diseases of the knee joint such as osteoarthritis (OA) affect all joint elements. An in vitro human cell‐derived microphysiological system capable of simulating intraarticular tissue crosstalk is desirable for studying etiologies/pathogenesis of joint diseases and testing potential therapeu...

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Bibliographic Details
Main Authors: Zhong Li, Zixuan Lin, Silvia Liu, Haruyo Yagi, Xiurui Zhang, Lauren Yocum, Monica Romero‐Lopez, Claire Rhee, Meagan J. Makarcyzk, Ilhan Yu, Eileen N. Li, Madalyn R. Fritch, Qi Gao, Kek Boon Goh, Benjamen O'Donnell, Tingjun Hao, Peter G. Alexander, Bhushan Mahadik, John P. Fisher, Stuart B. Goodman, Bruce A. Bunnell, Rocky S. Tuan, Hang Lin
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Advanced Science
Subjects:
arthritis
human mesenchymal stem cells
inflammation in joint
joint diseases
microphysiological system
Online Access:https://doi.org/10.1002/advs.202105909

Internet

https://doi.org/10.1002/advs.202105909

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