Soy Isoflavones Protect Neuronal PC12 Cells against Hypoxic Damage through Nrf2 Activation and Suppression of p38 MAPK and AKT–mTOR Pathways

Soy Isoflavones Protect Neuronal PC12 Cells against Hypoxic Damage through Nrf2 Activation and Suppression of p38 MAPK and AKT–mTOR Pathways

Isoflavones are a class of major phenolic compounds, derived from soybeans, that possess unique therapeutic and biological properties. The possible mechanisms of isoflavone-mediated protection of neuronal PC12 cells against hypoxic damage was investigated in this study. Isoflavones showed potential...

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Bibliographic Details
Main Authors: Yongzhu Zhang, Liqing Yin, Jiajia Dong, Xiudong Xia
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Antioxidants
Subjects:
phenolic compounds
neuroprotective effects
apoptosis
cell cycle
molecular docking analysis
Online Access:https://www.mdpi.com/2076-3921/11/10/2037

Internet

https://www.mdpi.com/2076-3921/11/10/2037

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