Stabilization of G-Quadruplex-Duplex Hybrid Structures Induced by Minor Groove-Binding Drugs

Once it had been realized that G-quadruplexes exist in the cell and are involved in regulation of genomic processes, the quest for ligands recognizing these noncanonical structures was underway. Many organic compounds that tightly associate with G-quadruplexes have been identified. However, the spec...

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Bibliographic Details
Main Authors: Lily Scott, Tigran V. Chalikian
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/4/597