PIEZO1 is downregulated in glenohumeral chondrocytes in early cuff tear arthropathy following a massive rotator cuff tear in a mouse model

PIEZO1 is downregulated in glenohumeral chondrocytes in early cuff tear arthropathy following a massive rotator cuff tear in a mouse model

Introduction: A massive rotator cuff tear (RCT) leads to glenohumeral joint destabilization and characteristic degenerative changes, termed cuff tear arthropathy (CTA). Understanding the response of articular cartilage to a massive RCT will elucidate opportunities to promote homeostasis following re...

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Bibliographic Details
Main Authors: Devon E. Anderson, Katherine G. Broun, Paromita Kundu, Xingyu Jing, Xiang Tang, Christopher Lu, Alexander Kotelsky, Sandeep Mannava, Whasil Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
articular cartilage
chondrocyte
rotator cuff tear (RCT)
cuff tear arthropathy (CTA)
PIEZO1 channel
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1244975/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1244975/full

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