Parkinson’s disease, epilepsy, and amyotrophic lateral sclerosis—emerging role of AMPA and kainate subtypes of ionotropic glutamate receptors

Parkinson’s disease, epilepsy, and amyotrophic lateral sclerosis—emerging role of AMPA and kainate subtypes of ionotropic glutamate receptors

Ionotropic glutamate receptors (iGluRs) mediate the majority of excitatory neurotransmission and are implicated in various neurological disorders. In this review, we discuss the role of the two fastest iGluRs subtypes, namely, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and kainate r...

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Bibliographic Details
Main Authors: Marina N. Vukolova, Laura Y. Yen, Margarita I. Khmyz, Alexander I. Sobolevsky, Maria V. Yelshanskaya
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
glutamate receptors
AMPA
Parkinson’s disease
epilepsy
ALS
kainate receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1252953/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1252953/full

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