Whole genome sequencing identifies candidate genes for familial essential tremor and reveals biological pathways implicated in essential tremor aetiology

Whole genome sequencing identifies candidate genes for familial essential tremor and reveals biological pathways implicated in essential tremor aetiology

Summary: Background: Essential tremor (ET), one of the most common neurological disorders, has a phenotypically heterogeneous presentation characterized by bilateral kinetic tremor of the arms and, in some patients, tremor involving other body regions (e.g., head, voice). Genetic studies suggest th...

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Bibliographic Details
Main Authors: Lorraine N. Clark, Yizhe Gao, Gao T. Wang, Nora Hernandez, Allison Ashley-Koch, Joseph Jankovic, Ruth Ottman, Suzanne M. Leal, Sandra M. Barral Rodriguez, Elan D. Louis
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:EBioMedicine
Subjects:
Essential tremor
Whole genome sequencing
Genome-wide linkage analysis
Multi-generation ET families
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422004728

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http://www.sciencedirect.com/science/article/pii/S2352396422004728

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