The E6 and E7 proteins of beta3 human papillomavirus 49 can deregulate both cellular and extracellular vesicles-carried microRNAs

Abstract Background The β3 human papillomavirus (HPV)49 induces immortalization of primary keratinocytes through the action of E6 and E7 oncoproteins with an efficiency similar to alpha high risk (HR)-HPV16. Since HR-HPV oncoproteins are known to alter microRNA (miRNA) expression and extracellular v...

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Bibliographic Details
Main Authors: Maria Vincenza Chiantore, Marco Iuliano, Roberta Maria Mongiovì, Sankhadeep Dutta, Massimo Tommasino, Paola Di Bonito, Luisa Accardi, Giorgio Mangino, Giovanna Romeo
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Infectious Agents and Cancer
Subjects:
Online Access:https://doi.org/10.1186/s13027-022-00445-z