The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae.

There is a pressing need for a gonorrhea vaccine due to the high disease burden associated with gonococcal infections globally and the rapid evolution of antibiotic resistance in Neisseria gonorrhoeae (Ng). Current gonorrhea vaccine research is in the stages of antigen discovery and the identificati...

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Main Authors: Isabelle Leduc, Kristie L Connolly, Afrin Begum, Knashka Underwood, Stephen Darnell, William M Shafer, Jacqueline T Balthazar, Andrew N Macintyre, Gregory D Sempowski, Joseph A Duncan, Marguerite B Little, Nazia Rahman, Eric C Garges, Ann E Jerse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008602