Centronuclear Myopathy Caused by Defective Membrane Remodelling of Dynamin 2 and BIN1 Variants

Centronuclear Myopathy Caused by Defective Membrane Remodelling of Dynamin 2 and BIN1 Variants

Centronuclear myopathy (CNM) is a congenital myopathy characterised by centralised nuclei in skeletal myofibers. T-tubules, sarcolemmal invaginations required for excitation-contraction coupling, are disorganised in the skeletal muscles of CNM patients. Previous studies showed that various endocytic...

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Bibliographic Details
Main Authors: Kenshiro Fujise, Satoru Noguchi, Tetsuya Takeda
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
centronuclear myopathy
T-tubules
dynamin
BIN1
membrane remodelling
Online Access:https://www.mdpi.com/1422-0067/23/11/6274

Internet

https://www.mdpi.com/1422-0067/23/11/6274

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