Vaccination with a chikungunya virus-like particle vaccine exacerbates disease in aged mice.

INTRODUCTION:Chikungunya virus (CHIKV) is a re-emerging pathogen responsible for causing outbreaks of febrile disease accompanied with debilitating joint pain. Symptoms typically persist for two weeks, but more severe and chronic chikungunya illnesses have been reported, especially in the elderly. C...

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Bibliographic Details
Main Authors: Maria T Arévalo, Ying Huang, Cheryl A Jones, Ted M Ross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6485612?pdf=render