Heparanase is the possible link between monkeypox and Covid-19: robust candidature in the mystic and present perspective

Abstract Heparanase (HPSE) is an endoglycosidase cleaves heparan sulfate (HS) and this contributes to the degradation and remodeling of the extracellular matrix. HS cleaved by HPSE induces activation of autophagy and formation of autophagosommes which facilitate binding of HPSE to the HS and subsequ...

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Bibliographic Details
Main Authors: Hayder M. Al-Kuraishy, Ali I. Al-Gareeb, ‏Helal F. Hetta, Athanasios Alexiou, Marios Papadakis, Gaber El-Saber Batiha
Format: Article
Language:English
Published: SpringerOpen 2023-01-01
Series:AMB Express
Subjects:
Online Access:https://doi.org/10.1186/s13568-023-01517-y