S-Nitrosylated hemoglobin predicts organ yield in neurologically-deceased human donors

Abstract Current human donor care protocols following death by neurologic criteria (DNC) can stabilize macro-hemodynamic parameters but have minimal ability to preserve systemic blood flow and microvascular oxygen delivery. S-nitrosylated hemoglobin (SNO-Hb) within red blood cells (RBCs) is the main...

Full description

Bibliographic Details
Main Authors: Ryan Nazemian, Maroun Matta, Amer Aldamouk, Lin Zhu, Mohamed Awad, Megan Pophal, Nicole R. Palmer, Tonya Armes, Alfred Hausladen, Jonathan S. Stamler, James D. Reynolds
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-09933-z