Engineering the Yeast Saccharomyces cerevisiae for the Production of L-(+)-Ergothioneine

Engineering the Yeast Saccharomyces cerevisiae for the Production of L-(+)-Ergothioneine

L-(+)-Ergothioneine (ERG) is an unusual, naturally occurring antioxidant nutraceutical that has been shown to help reduce cellular oxidative damage. Humans do not biosynthesise ERG, but acquire it from their diet; it exploits a specific transporter (SLC22A4) for its uptake. ERG is considered to be a...

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Bibliographic Details
Main Authors: Steven A. van der Hoek, Behrooz Darbani, Karolina E. Zugaj, Bala Krishna Prabhala, Mathias Bernfried Biron, Milica Randelovic, Jacqueline B. Medina, Douglas B. Kell, Irina Borodina
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
ergothioneine
metabolic engineering
medium optimization
Saccharomyces cerevisiae
yeast
nutraceutical
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00262/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2019.00262/full

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