Physiological function of polyploid hepatocytes and pathological changes in its associated diseases

Liver is a unique organ with polyploidy. About 20 to 50 percent of hepatocytes in adult human are polyploid cells, which contain more than two sets of chromosomes. Hepatocytes polyploidization is triggered by the changes in insulin signal during weaning, and regulated by various cell cycle regulator...

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Bibliographic Details
Main Author: ZHANG Yifan, LU Yiquan, HAO Fengjie, WANG Junqing
Format: Article
Language:zho
Published: Editorial Office of Journal of Surgery Concepts & Practice 2023-11-01
Series:Waike lilun yu shijian
Subjects:
Online Access:https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1709530094042-2010220622.pdf