Maternal Western diet exposure increases periportal fibrosis beginning in utero in nonhuman primate offspring

Maternal Western diet exposure increases periportal fibrosis beginning in utero in nonhuman primate offspring

Maternal obesity affects nearly one-third of pregnancies and is a major risk factor for nonalcoholic fatty liver disease (NAFLD) in adolescent offspring, yet the mechanisms behind NAFLD remain poorly understood. Here, we demonstrate that nonhuman primate fetuses exposed to maternal Western-style die...

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Bibliographic Details
Main Authors: Michael J. Nash, Evgenia Dobrinskikh, Sean A. Newsom, Ilhem Messaoudi, Rachel C. Janssen, Kjersti M. Aagaard, Carrie E. McCurdy, Maureen Gannon, Paul Kievit, Jacob E. Friedman, Stephanie R. Wesolowski
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-12-01
Series:JCI Insight
Subjects:
Gastroenterology
Online Access:https://doi.org/10.1172/jci.insight.154093

Internet

https://doi.org/10.1172/jci.insight.154093

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