Development of a novel radiofluorinated riboflavin probe for riboflavin receptor-targeting PET imaging

Development of a novel radiofluorinated riboflavin probe for riboflavin receptor-targeting PET imaging

Riboflavin receptor 3 (RFVT3) is a key protein in energetic metabolism reprogramming and is overexpressed in multiple cancers involved in malignant proliferation, angiogenesis, chemotherapy resistance, and immunosuppression. To enable non-invasive real-time quantification of RFVT3 in tumors, we soug...

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Bibliographic Details
Main Authors: Jindian Li, Juno Van Valkenburgh, Jianyang Fang, Deliang Zhang, Yingxi Chen, Quan Chen, Guorong Jia, Austin Z. Chen, Xianzhong Zhang, Kai Chen
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Pharmacological Research
Subjects:
Riboflavin receptor 3
Riboflavin
Positron emission tomography
Pharmacology
Probe development
Cancer imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661822003401

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http://www.sciencedirect.com/science/article/pii/S1043661822003401

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