Photoactivatable mRNA 5′ Cap Analogs for RNA‐Protein Crosslinking

Photoactivatable mRNA 5′ Cap Analogs for RNA‐Protein Crosslinking

Abstract Chemical modification of messenger RNA (mRNA) has paved the way for advancing mRNA‐based therapeutics. The intricate process of mRNA translation in eukaryotes is orchestrated by numerous proteins involved in complex interaction networks. Many of them bind specifically to a unique structure...

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Bibliographic Details
Main Authors: Marcin Warminski, Katarzyna Grab, Kacper Szczepanski, Tomasz Spiewla, Joanna Zuberek, Joanna Kowalska, Jacek Jemielity
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:Advanced Science
Subjects:
5′ cap
cap‐binding proteins
mRNA
photoaffinity labeling
photocrosslinking
Online Access:https://doi.org/10.1002/advs.202400994

Internet

https://doi.org/10.1002/advs.202400994

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