Functional Distinctions of Endometrial Cancer-Associated Mutations in the Fibroblast Growth Factor Receptor 2 Gene

Functional Distinctions of Endometrial Cancer-Associated Mutations in the Fibroblast Growth Factor Receptor 2 Gene

Functional analysis of somatic mutations in tumorigenesis facilitates the development and optimization of personalized therapy for cancer patients. The <i>fibroblast growth factor receptor 2</i> (<i>FGFR2</i>) gene is frequently mutated in endometrial cancer (EC), but the fun...

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Bibliographic Details
Main Authors: Garima Dixit, Benjamin A. Pappas, Gourav Bhardwaj, Willow Schanz, Thorsten Maretzky
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cells
Subjects:
a disintegrin and metalloprotease 17 (ADAM17)
fibroblast growth factor receptor 2 (FGFR2)
epidermal growth factor receptor (EGFR)
heparin-binding EGF-like growth factor (HB-EGF)
endometrial cancer (EC)
Online Access:https://www.mdpi.com/2073-4409/12/18/2227

Internet

https://www.mdpi.com/2073-4409/12/18/2227

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