Effect of transverse aortic constriction on cardiac structure, function and gene expression in pregnant rats.

BACKGROUND: There is an increased risk of heart failure and pulmonary edema in pregnancies complicated by hypertensive disorders. However, in a previous study we found that pregnancy protects against fibrosis and preserves angiogenesis in a rat model of angiotensin II induced cardiac hypertrophy. In...

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Bibliographic Details
Main Authors: Nils Thomas Songstad, David Johansen, Ole-Jacob How, Per Ivar Kaaresen, Kirsti Ytrehus, Ganesh Acharya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3930736?pdf=render