Cholecystectomy prevents expansion of the bile acid pool and inhibition of cholesterol 7α-hydroxylase in rabbits fed cholesterol

Cholecystectomy prevents expansion of the bile acid pool and inhibition of cholesterol 7α-hydroxylase in rabbits fed cholesterol

To study the effect of cholecystectomy on the regulation of classic and alternative bile acid syntheses, gallbladder-intact (n = 20) and cholecystectomized (n = 20) New Zealand White rabbits were fed either chow or chow with 2% cholesterol (3 g/day). After 10 days, bile fistulas were constructed in...

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Bibliographic Details
Main Authors: Guorong Xu, Gerald Salen, Benjamin L. Shneider, M. Ananthanarayanan, Sarah Shefer, Lin Ma, Ashok Batta, Lien B. Nguyen, Josephine J. Lingutla, G. Stephen Tint, Mark Pcolinsky, Frederick J. Suchy
Format: Article
Language:English
Published: Elsevier 2001-09-01
Series:Journal of Lipid Research
Subjects:
apical sodium-dependent bile acid transporter
sodium/taurocholate cotransporting polypeptide
bile acid synthesis
cholesterol 27-hydroxylase
bile acid transport
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520302765

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http://www.sciencedirect.com/science/article/pii/S0022227520302765

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