The Hippo signaling pathway contributes to the 2,5-Hexadion-induced apoptosis of ovarian granulosa cells

The Hippo signaling pathway contributes to the 2,5-Hexadion-induced apoptosis of ovarian granulosa cells

Abstract Although n-hexane can induce ovarian damage by inducing ovarian granulosa cell (GC) apoptosis, the mechanism underlying this induction of apoptosis has not been fully elucidated. In this study, rat ovarian GCs were exposed to different concentrations of 2,5-hexanedione (2,5-HD) (the main me...

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Bibliographic Details
Main Authors: Yi Sun, Huiting Chen, Sichuan Chen, Xueming Xu, Wenchang Zhang, Yuchen Li
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Ovarian Research
Subjects:
2,5-hexanedione
Ovarian granulosa cells
Hippo signaling pathway
Apoptosis
mRNA expression microarray
Online Access:https://doi.org/10.1186/s13048-023-01249-4

Internet

https://doi.org/10.1186/s13048-023-01249-4

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