Ameliorating effects of Gö6976, a pharmacological agent that inhibits protein kinase D, on collagen-induced arthritis.

Ameliorating effects of Gö6976, a pharmacological agent that inhibits protein kinase D, on collagen-induced arthritis.

Toll-like receptor (TLR) signaling can contribute to the pathogenesis of arthritis. Disruption of TLR signaling at early stages of arthritis might thereby provide an opportunity to halt the disease progression and ameliorate outcomes. We previously found that Gö6976 inhibits TLR-mediated cytokine pr...

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Bibliographic Details
Main Authors: Tae Won Yoon, Young-In Kim, Hongsik Cho, David D Brand, Edward F Rosloniec, Linda K Myers, Arnold E Postlethwaite, Karen A Hasty, John M Stuart, Ae-Kyung Yi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226145

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https://doi.org/10.1371/journal.pone.0226145

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