Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability

Thrombospondin 4 has been shown to protect the heart and the skeletal muscle by enhancing matrix secretion and membrane stability thanks to its intracellular function. Here the authors show that thrombospondin 3 exacerbates injury-induced cardiomyopathy and promotes destabilization of the cardiomyoc...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Tobias G. Schips, Davy Vanhoutte, Alexander Vo, Robert N. Correll, Matthew J. Brody, Hadi Khalil, Jason Karch, Andoria Tjondrokoesoemo, Michelle A. Sargent, Marjorie Maillet, Robert S. Ross, Jeffery D. Molkentin
स्वरूप: लेख
भाषा:English
प्रकाशित: Nature Portfolio 2019-01-01
श्रृंखला:Nature Communications
ऑनलाइन पहुंच:https://doi.org/10.1038/s41467-018-08026-8