Strategies to overcome tumor microenvironment immunosuppressive effect on the functioning of CAR-T cells in high-grade glioma

Despite significant progress in the treatment of some types of cancer, high-grade gliomas (HGGs) remain a significant clinical problem. In the case of glioblastoma (GBM), the most common solid tumor of the central nervous system in adults, the average survival time from diagnosis is only 15–18 month...

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Bibliographic Details
Main Authors: Julia Zarychta, Adrian Kowalczyk, Anna Marszołek, Joanna Zawitkowska, Monika Lejman
Format: Article
Language:English
Published: SAGE Publishing 2024-08-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/17588359241266140