Evidence for a Strong Relationship between the Cytotoxicity and Intracellular Location of β-Amyloid
β-Amyloid (Aβ) is a hallmark peptide of Alzheimer’s disease (AD). Herein, we explored the mechanism underlying the cytotoxicity of this peptide. Double treatment with oligomeric 42-amino-acid Aβ (Aβ42) species, which are more cytotoxic than other conformers such as monomers and fibrils, resulted in...
Main Authors: | Md. Aminul Haque, Md. Selim Hossain, Tahmina Bilkis, Md. Imamul Islam, Il-Seon Park |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-04-01
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Series: | Life |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-1729/12/4/577 |
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