Leptin and environmental temperature as determinants of bone marrow adiposity in female mice

Bone marrow adipose tissue (BMAT) levels are higher in distal femur metaphysis of female mice housed at thermoneutral (32°C) than in mice housed at 22°C, as are abdominal white adipose tissue (WAT) mass, and serum leptin levels. We performed two experiments to explore the role of increased leptin in...

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Bibliographic Details
Main Authors: Russell T. Turner, Kira L. Nesser, Kenneth A. Philbrick, Carmen P. Wong, Dawn A. Olson, Adam J. Branscum, Urszula T. Iwaniec
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.959743/full