Synthesis and Monoamine Oxidase Inhibition Properties of 4-(2-Methyloxazol-4-yl)benzenesulfonamide

Synthesis and Monoamine Oxidase Inhibition Properties of 4-(2-Methyloxazol-4-yl)benzenesulfonamide

4-(2-Methyloxazol-4-yl)benzenesulfonamide was synthesized by the reaction of 4-(2-bromoacetyl)benzenesulfonamide with an excess of acetamide. The compound was evaluated as a potential inhibitor of human monoamine oxidase (MAO) A and B and was found to inhibit these enzymes with IC<sub>50</s...

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Bibliographic Details
Main Authors: Anton A. Shetnev, Julia A. Efimova, Mikhail K. Korsakov, Anél Petzer, Jacobus P. Petzer
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molbank
Subjects:
monoamine oxidase
MAO
inhibitor
1,3-oxazole
benzenesulfonamide
drug research
Online Access:https://www.mdpi.com/1422-8599/2024/1/M1787

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https://www.mdpi.com/1422-8599/2024/1/M1787

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