H5N1 influenza vaccine quality is affected by hemagglutinin conformational stability
Since 1997, highly pathogenic H5N1 avian influenza viruses have circulated in wild and domestic birds and sporadically have infected humans. Conventional inactivated vaccines made from these viruses were shown to have decreased HA content and immunogenicity compared to seasonal preparations. We assu...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Doctrine
2014-01-01
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Series: | Microbiology Independent Research Journal |
Online Access: | https://www.scienceopen.com/hosted-document?doi=10.18527/2500-2236-2014-1-1-12-26 |