Dual-targeting AAV9P1-mediated neuronal reprogramming in a mouse model of traumatic brain injury

Dual-targeting AAV9P1-mediated neuronal reprogramming in a mouse model of traumatic brain injury

[INLINE:1] Traumatic brain injury results in neuronal loss and glial scar formation. Replenishing neurons and eliminating the consequences of glial scar formation are essential for treating traumatic brain injury. Neuronal reprogramming is a promising strategy to convert glial scars to neural tissue...

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Bibliographic Details
Main Authors: Jingzhou Liu, Xin Xin, Jiejie Sun, Yueyue Fan, Xun Zhou, Wei Gong, Meiyan Yang, Zhiping Li, Yuli Wang, Yang Yang, Chunsheng Gao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Neural Regeneration Research
Subjects:
aav9p1; astrocytes; astrocyte-to-neuron conversion; gfap promoter; glial scar; induced neurons; neuronal reprogramming; p1 peptide; ptbp1; traumatic brain injury
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=3;spage=629;epage=635;aulast=Liu

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=3;spage=629;epage=635;aulast=Liu

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