Muscular myostatin gene expression and plasma concentrations are decreased in critically ill patients

Muscular myostatin gene expression and plasma concentrations are decreased in critically ill patients

Abstract Background The objective was to investigate the role of gene expression and plasma levels of the muscular protein myostatin in intensive care unit-acquired weakness (ICUAW). This was performed to evaluate a potential clinical and/or pathophysiological rationale of therapeutic myostatin inhi...

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Bibliographic Details
Main Authors: Julius J. Grunow, Katja Reiher, Niklas M. Carbon, Lilian Jo Engelhardt, Knut Mai, Susanne Koch, Joerg C. Schefold, Werner Z’Graggen, Stefan J. Schaller, Jens Fielitz, Joachim Spranger, Steffen Weber-Carstens, Tobias Wollersheim
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Critical Care
Subjects:
Myostatin
ICUAW
Muscle atrophy
Insulin resistance
Critical illness
Online Access:https://doi.org/10.1186/s13054-022-04101-1

Internet

https://doi.org/10.1186/s13054-022-04101-1

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