THE ACTIVATION OF MATRIX METALLOPROTEINASES AND CHONDROCYTE DIFFERENTIATION, WHICH ACCOMPANIES THE INDUCTION OF COLLAGEN DECOMPOSITION UNDER THE ACTION OF COLLAGEN PEPTIDE IN THE CARTILAGE OFHEALTHY INDIVIDUALS

THE ACTIVATION OF MATRIX METALLOPROTEINASES AND CHONDROCYTE DIFFERENTIATION, WHICH ACCOMPANIES THE INDUCTION OF COLLAGEN DECOMPOSITION UNDER THE ACTION OF COLLAGEN PEPTIDE IN THE CARTILAGE OFHEALTHY INDIVIDUALS

Objective: To study the effect of type II collagen peptide (CB12-2) that is able to induce the collagen decomposition in the knee articular cartilage explants, which activates matrix metalloproteinase (MMP) and articular chondrocyte differentiation. Material and methods. Human cartilage explants wer...

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Bibliographic Details
Main Authors: Elena Vasil'evna Chetina, Elena Vasilyevna Chetina
Format: Article
Language:Russian
Published: IMA PRESS LLC 2010-10-01
Series:Научно-практическая ревматология
Subjects:
articular cartilage
gene expression
chondrocyte hypertrophy
collagenase
type ii collagen
peptide
Online Access:https://rsp.mediar-press.net/rsp/article/view/868

Internet

https://rsp.mediar-press.net/rsp/article/view/868

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